How to improve your insulin response

Let’s talk about insulin

Insulin is a hormone secreted by the pancreas in response to a rise in blood sugar levels. Although insulin is most known for its role in regulating blood glucose levels, it also influences fat and protein metabolism (more on this in a moment).

When you eat a carbohydrate containing meal your blood glucose levels will rise, causing the pancreas to release insulin to normalise blood glucose levels. It is an elegant system and, when working effectively, helps to maintain healthy levels of blood sugar.

When things go amiss

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Sometimes cells will stop responding to insulin correctly, meaning that the pancreas produces more insulin to normalise blood sugar levels.   We call this condition insulin resistance.Over time cells can become increasingly resistant to the effects of insulin: causing chronic rises in both insulin and blood glucose levels.  This can result in the pancreas becoming damaged from overuse, leading to decreased insulin production.  The resultant rise in blood sugar levels will be diagnosed as type 2 diabetes if levels exceed a certain threshold. 


Why do cells become insulin resistant?

Overconsumption of calories and the carrying of excess body fat can cause a rise in the level of free fatty acids in the blood. This is particularly the case with visceral fat (the fat found around organs) which has been shown to release fatty acids and inflammatory hormones, which facilitate insulin resistance, into the blood.

The majority of current research points to the prevalence of high amounts of free fatty acids in the blood as the major culprit in the development of insulin resistance.


Diabetes is not the only concern

The development of type 2 diabetes isn’t the only concern that flows from insulin resistance. 

Metabolic syndrome

Metabolic syndrome, characterised by high blood triglycerides, high blood pressure, excess abdominal fat, high blood sugar and low HDL (good) cholesterol levels, can also develop out of insulin resistance.

Weight gain

Insulin promotes the reduction of blood glucose levels through several mechanisms. Notably, it will switch on mechanisms for the storage of body fat (lipogenesis) and switch off mechanisms for the utilisation of body fat as energy (lipolysis).  It is for this reason that insulin resistant individuals are predisposed to weight gain far greater than insulin sensitive individuals.
 

Others

Heart disease, non-alcoholic fatty liver disease, polycystic ovarian syndrome, Alzheimer’s disease, and various form of cancer have all been linked to high levels of insulin resistance.

At risk groups

Inactive individuals, particularly those who are overweight or obese are most at risk.   However there is some evidence certain ethnic groups (black, Hispanic and Asian) may also be at increased risk for genetic and cultural reasons.

 

What can I do?

We all lie on a spectrum of insulin sensitivity to insulin resistance.   Fortunately, there are a number of simple lifestyle changes one can implement to increase their insulin sensitivity and move away from potentially dangerous levels of insulin resistance.

NOTE – if you are diabetic consult your physician before engaging in dietary or lifestyle changes.

Exercise

This is likely the most effective method for quickly improving insulin sensitivity. (19) In many cases results flowing after only a few weeks of engagement in exercise.  Of particular value in this context may be weight bearing exercise, as individuals with larger amounts of muscle mass tend to utilise carbohydrate more effectively.

Although significant, it should be noted that exercise alone will not likely be an effective way of improving insulin sensitivity in the long term. However, when combined with dietary interventions, long term results will likely result.

Reduce sugar intake

If your ability to effectively regulate blood sugar is compromised it follows that there will be benefit to reducing sugar intake.   Once insulin sensitivity is increased sugar can then be reintroduced into the diet gradually. (Although it is generally recommend that a healthy diet will contain minimal processed and refined sugars)

Quit smoking

Contrary to the cultural adage that smoking ‘keeps you thin’ - smoking has been proven to increase insulin resistance and lead to weight gain over the long term.

Improve sleep and reduce stress

Easier said than done I know (as I write this I have an 8 month old daughter who seems to have decided sleep is for the weak).  However, it is worth noting that reducing stress and improving sleep quality have both been shown to improve insulin sensitivity.

Intermittent Fasting

Intermittent fasting – where individuals restrict their food intake to a pre-determined ‘eating window’ – has been shown to be efficacious in increasing insulin sensitivity. In my experience this tends to be the most effective and most sustainable method of making meaningful change in this area. However, please be cautious, many of the benefits proposed by internet and commercial proponents of intermittent fasting are often overblown and not fully backed up by current research. (it will not fix all of your health problems while cleaning your house and doing your taxes)

For full disclosure, I use intermittent fasting as part of my eating pattern. I find it does wonders for my energy levels and helps me maintain a healthy weight with ease. If you wish to give it a try I would recommend a 16/8 fast where you eat all your daily food in an 8 hour window, 12pm to 8pm for example. My experience is that this works brilliantly for many, less well for some. So if you try it and don’t find benefit it simply might not be the best eating pattern for you.

Low-carbohydrate diets

Likewise, low carbohydrate diets (eg. atkins or keto) can be very effective at improving insulin sensitivity. However, in my experience, very low carbohydrate diets tend to be unsustainable for a long period of time.  Further, if not curated effectively they often end up being deficient in various nutrients and essential dietary components - most notably fibre.   I would recommend utilising a low carbohydrate eating plan for a short period of time to gain desired effect, and then begin introducing complex carbohydrates back into the diet.

 

My personal experience

My anecdotal experience working with clients suggests that a multitude of benefits will flow from focusing on improving insulin response. On the flip side, an insulin resistant client will struggle to manage hunger, energy levels and maintain a healthy weight.

If you are someone who feels lethargic often, craves sugary foods regularly and puts on weight easily it is possible you may lie somewhere on the insulin resistant end of the spectrum.  It may be valuable to implement a few focused changes to your dietary habits and lifestyle to reap the benefits of insulin sensitivity and avoid the potential of allowing the problem to develop into type 2 diabetes.

Feed the life you want to lead,

Duncan

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